Oncology & Cancer

Researchers identify new targets for immunotherapy in colon cancer

Colon cancer is one of the most common types of cancer. Particularly in advanced stages of disease, the treatment still largely relies on traditional chemotherapy. The new generation of cancer treatments, so-called immunotherapies, ...

Neuroscience

Hungry or full: It comes down to the atomic details

A protein—measuring just a few nanometers in size—acts as a molecular switch with a crucial role in determining whether we feel hungry or full. By determining of the protein's 3-D structure, researchers from Charité ...

Psychology & Psychiatry

STAT3 identified as important factor in emotional reactivity

Numerous scientific studies indicate that inflammatory processes play a key role in the development of psychiatric disorders. One of the areas of particular interest is the interleukin 6/STAT3 signal transduction pathway, ...

Medical research

New insights provide hope for new hair growth in adults

We are born with all the hair follicles that we will ever have in our lives, because after birth the skin loses the ability to create new hair follicles. If our skin is severely damaged it cannot form new hair follicles or ...

Cardiology

A molecular atlas of postnatal mouse heart development

Myocardial infarction (MI) is one of the most common causes of death in the Western world. Typically, MI is caused by the blockage of a coronary artery by an atherosclerotic plaque: as the oxygen supply of the heart drops, ...

Medical research

Crosstalk between cells plays role in pulmonary hypertension

Pulmonary hypertension is a type of high blood pressure that affects blood vessels in the lungs. Once diagnosed, patients have limited treatment options, and many do not live beyond seven years. In a new study, scientists ...

Medical research

Profiling the gut microbiome proteins that modify bile

It turns out that bile is a lot more dynamic than you might think. One of the biggest factors affecting bile, which is very important to our ability to absorb nutrients, is our diet. But another is the make-up of the community ...

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