More than 20 years after scientists revealed that mutations in the BRCA1 gene predispose women to breast cancer, Yale scientists have pinpointed the molecular mechanism that allows those mutations to wreak their havoc.
Oct 4, 2017
0
26
(Medical Xpress)—A new study from researchers at the University of Florida may have uncovered a critical factor that drives the relentless progression of Alzheimer's disease ― a discovery that could eventually slow its ...
Apr 16, 2013
0
0
(Medical Xpress)—A new study by researchers at the Center for Modeling Immunity to Enteric Pathogens at Virginia Bioinformatics Institute provides novel insight into how an emerging strain of the diarrhea-causing bacteria ...
Mar 28, 2013
0
0
Botox is best known for its use in cosmetic procedures, but this potent neurotoxin could be transformed into an extraordinary drug to treat a raft of debilitating conditions, a leading scientist will tell an audience at the ...
Mar 15, 2013
0
0
For many inherited diseases, such as cystic fibrosis or Huntington disease, the disease-causing genetic mutation damages or removes a protein that has an essential role in the body. This protein defect is the root cause of ...
Aug 8, 2013
0
0
Researchers report that a drug targeting the cancer-causing gene MYC inhibits the function of the gene in a phase I clinical trial. Until now, no other drug has been able to do this safely and effectively.
Oct 26, 2022
0
10
Findings from preclinical studies in a skin cancer model showed that next-generation BRAF inhibitors used alone, or first-generation BRAF inhibitors used in combination with an epidermal growth factor receptor inhibitor, ...
Nov 13, 2011
0
0
A new study, published today in Nature Structural and Molecular Biology, moves researchers closer to understanding one of the crucial proteins involved in Parkinson's disease.
Jul 4, 2018
0
6
Cancer occurs when cells grow uncontrollably and spread to other organs in the body. Cancer cells differ from normal cells in many ways. One characteristic of cancer cells is their high adaptability to different environments ...
Sep 21, 2022
0
78
British researchers have identified specific resistance mutations for two classes of p7 inhibitor, which may explain their lack of effectiveness in clinical trials combined with current standard of care. Study results support ...
Jun 28, 2011
0
0
