Oncology & Cancer
New class of drugs could help tackle treatment-resistant cancers
Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies.
Apr 10, 2018
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Page 6 - News tagged with molecular therapeutics
Other
Nobel Prize winner says scientific research has to be 'passion-driven'
Scientists cannot be expected to drop everything they're working on to turn their attention to beating COVID-19, according to the winner of the 2019 Nobel Prize in Physiology or Medicine, Professor Sir Peter Ratcliffe.
Oct 23, 2020
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Parkinson's & Movement disorders
Study points to possible cause of, and treatment for, non-familial Parkinson's
Columbia University Medical Center (CUMC) researchers have identified a protein trafficking defect within brain cells that may underlie common non-familial forms of Parkinson's disease. The defect is at a point of convergence ...
Feb 6, 2013
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Oncology & Cancer
Researchers map potential genetic origins, pathways of lung cancer in nonsmokers
Researchers at the Translational Genomics Research Institute (TGen) have begun to identify mutations and cellular pathway changes that lead to lung cancer in never-smokers -- a first step in developing potential therapeutic ...
Jan 9, 2012
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Oncology & Cancer
New therapeutic target to combat liver cancer discovered
Spanish researchers at CIC Biogune, the Cooperative Centre for Research into Biosciences and led by Dr. Maria Luz Martinez Chantar, have found a strong relationship between high levels of Hu antigen R (HuR) protein and the ...
Jan 26, 2012
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Oncology & Cancer
Researchers find new, noninvasive way to identify lymph node metastasis
Using two cell surface markers found to be highly expressed in breast cancer lymph node metastases, researchers at Moffitt Cancer Center, working with colleagues at other institutions, have developed targeted, fluorescent ...
Jan 12, 2012
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Oncology & Cancer
The behavior of therapeutic antibodies in immunotherapy
Since the late 1990s, immunotherapy has been the frontline treatment against lymphomas where synthetic antibodies are used to stop the proliferation of cancerous white blood cells. However, in the more than 20 years since ...
Aug 13, 2020
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Oncology & Cancer
A new class of drug slows growth of castration-resistant prostate cancer cells
A first-in-class sphingosine kinase 2 inhibitor slowed the growth of castration-resistant prostate cancer cells, in part by inhibiting the enzyme dihydroceramide desaturase (DEGS), but did not kill them, according to the ...
Jan 29, 2016
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Medical research
Scientists identify the causes of cortisone induced side effects
Patients undergoing long-term treatment with steroids may suffer from metabolic side effects. Researchers at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich (LMU), partners in the German Center ...
Jan 25, 2019
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Oncology & Cancer
Two targeted therapies act against Ewing's sarcoma tumors
A pair of targeted therapies shrank tumors in some patients with treatment-resistant Ewing's sarcoma or desmoplastic small-round-cell tumors, according to research led by investigators from The University of Texas MD Anderson ...
Apr 1, 2012
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