For many inherited diseases, such as cystic fibrosis or Huntington disease, the disease-causing genetic mutation damages or removes a protein that has an essential role in the body. This protein defect is the root cause of ...
Aug 8, 2013
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Australian researchers have worked out how to fix a defect that causes lupus, and hope their world-first discovery will offer effective long-term treatment.
Feb 6, 2024
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Brain injuries cause widespread damage to brain tissue. Damaged cells begin to produce signaling molecules that trigger processes of inflammation, apoptosis—programmed cell death—and oxidative stress. After the acute ...
Jan 18, 2024
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Siglec-15 has emerged as a promising target for therapeutic intervention in the field of cancer treatment, primarily due to its unique expression pattern and potential as an immune modulator. Its distinct expression profile, ...
Jun 16, 2023
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Van Andel Institute scientists have pinpointed how a specific gene mutation triggers an inflammatory cascade that may drive development of treatment-resistant cancers.
May 11, 2023
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Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal genetic disease—about a half million people in the United States alone suffer from the condition. There is no cure, but new research ...
Apr 3, 2023
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Northwestern Medicine investigators have discovered novel sex-specific mechanisms that control how stress hormones impact dopamine transmission and motivation, findings that can inform new therapeutic strategies for treating ...
Mar 24, 2023
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Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, collaborating with international researchers, have developed a sophisticated AI algorithm that performs advanced computational ...
Feb 2, 2023
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Cancer occurs when cells grow uncontrollably and spread to other organs in the body. Cancer cells differ from normal cells in many ways. One characteristic of cancer cells is their high adaptability to different environments ...
Sep 21, 2022
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Chimeric antigen receptor T-cell therapy, or CAR T, has made a big impact on the treatment of certain blood cancers, allowing patients with relapsed/refractory disease to live longer, healthier lives. But in clinical study, ...
May 5, 2022
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