Medical research

Liver fibrosis: The fatal signaling pathway

At least 5 million people in Germany suffer from liver disease. Fibrosis, the pathological proliferation of connective tissue, plays an important role in many complications of chronic liver problems. Activated hepatic stellate ...

Alzheimer's disease & dementia

New Alzheimer's biomarker may facilitate rapid diagnosis

Although symptoms of advanced Alzheimer's disease are well known, diagnosis of Alzheimer's disease in its earliest stages requires careful cognitive testing by neurologists.

Neuroscience

Widespread brain receptor hides surprising mechanism of action

One of the most important molecules in the brain doesn't work quite the way scientists thought it did, according to new work by researchers at Columbia University Vagelos College of Physicians and Surgeons and Carnegie Mellon ...

Medical research

Unexpected protein could play role in common brain disorder

Scientists have known for years that amyloid fibrils—fibrous, ropelike structures formed by closely linked protein molecules—are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play ...

Immunology

Double-stranded RNA induces bone loss during gum disease

Tokyo University of Agriculture and Technology researchers reported on a new discovery regarding the mechanisms for bone loss in gum disease (periodontitis). They found that double stranded RNA molecules can activate the ...

Medical research

Researchers use RNA to target pancreatic beta cells

Investigators at the University of Miami Miller School of Medicine have designed RNA molecules that home to human pancreatic beta cells, the cells that produce insulin and are destroyed in patients with type 1 and type 2 ...

Oncology & Cancer

Epigenetic study provides new insights into the origins of glioma

MicroRNA-10b (miR-10b) is a regulatory molecule that is silenced in normal cells of the brain but becomes abundant in more than 90 percent of high-grade gliomas. Glioblastomas (GBM) — the highest grade of glioma — appear ...

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