Boosting one gene in the brain's helper cells slows Alzheimer's progression in mice
Increasing the expression of one gene in cells that assist the brain's neurons protects neurons in mouse models of Alzheimer's disease.
Jan 11, 2022
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Increasing the expression of one gene in cells that assist the brain's neurons protects neurons in mouse models of Alzheimer's disease.
Jan 11, 2022
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84
In preclinical studies, Mayo Clinic scientists and collaborators have identified the molecular mechanism used by the brain's "cleaners" as they remove a problematic protein in the brain. This work, published in Nature Neuroscience, ...
Jan 4, 2022
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Myelin, a sheath of insulation around nerves that enables electrical impulses to efficiently travel through the central nervous system, is diminished in mice that have a gene deletion associated with autism spectrum disorder, ...
Dec 21, 2021
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Glioblastoma is widely considered the most aggressive brain cancer. Even with treatment, patient survival rates are low, with most living an average of 15–18 months after diagnosis. Because of the highly diverse characteristics ...
Dec 21, 2021
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Researchers at Uppsala University have used AI to develop a new method to study brain cancer. The method is based on transplanting tumor cells from patients to fish embryos, followed by observation with AI. The method, which ...
Dec 20, 2021
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Using new methodology, University of Kentucky researchers have mapped the variations in sugar chains attached to brain proteins from deceased healthy individuals or individuals with Alzheimer's disease.
Dec 16, 2021
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A characteristic of depression is a lack of motivation. Cold Spring Harbor Laboratory (CSHL) Professor Bo Li, in collaboration with CSHL Adjunct Professor Z. Josh Huang, discovered a group of neurons in the mouse brain that ...
Dec 9, 2021
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Just as a home security system can alert a homeowner to the presence of an intruder, a protein called polyglutamine binding protein-1 (PQBP1) found in brain cells can alert the body to the presence of "intruding" viruses ...
Dec 8, 2021
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Though many people with autism spectrum disorders also experience unusual gastrointestinal inflammation, scientists have not established how those conditions might be linked. Now Harvard Medical School and MIT researchers, ...
Dec 7, 2021
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The blood-brain barrier is an essential and meticulous protector of the human body. This highly selective gatekeeper of interlocking endothelial cells forms tight junctions, shielding vulnerable brains cells from toxins in ...
Dec 6, 2021
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