Diseases, Conditions, Syndromes

Children with Alagille Syndrome have malformed bile ducts

Serious liver and heart problems can affect children with Alagille Syndrome early in life. While there is as yet no cure, researchers at Karolinska Institutet in Sweden have discovered that the liver disease part of the syndrome ...

Cardiology

Scientists reverse advanced heart failure in an animal model

Researchers have discovered a previously unrecognized healing capacity of the heart. In a mouse model, they were able to reverse severe heart failure by silencing the activity of Hippo, a signaling pathway that can prevent ...

Oncology & Cancer

A tumor-suppressing gene can be harmful in some cancers

The TET2 tumor suppressor gene helps guard against blood cancers and perhaps protects against heart disease. Mutations in the gene affect about 1% of people over the age of 65, making them more susceptible to those diseases. ...

Cardiology

Study hints at experimental therapy for heart fibrosis

Researchers report encouraging preclinical results as they pursue elusive therapeutic strategies to repair scarred and poorly functioning heart tissues after cardiac injury—describing an experimental molecular treatment ...

Cardiology

Heart tissues of different origins can 'beat' in sync

Researchers from MIPT and the University of Bonn have shown that heart tissues of different origins can contract in sync. In a series of experiments, they first merged two rat tissues of different ages and then combined rat ...

Cardiology

Study identifies key player in heart enlargement

The heart is a dynamic muscle that grows and shrinks in response to stressors such as exercise and disease. The secret to its malleability lies in individual cells, which get bigger or smaller depending on the heart's needs. ...

Genetics

Discovery of a key regulatory gene in cardiac valve formation

Researchers from the University of Basel in Switzerland have identified a key regulator gene for the formation of cardiac valves - a process crucial to normal embryonic heart development. These results are published in the ...

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