As humans age, hematopoietic stem cells—the immature precursor cells that give rise to all blood and immune cells—accumulate mutations. Some of the mutations allow these stem cells to self-renew and expand more effectively ...
Jun 5, 2024
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A team of scientists at the Broad Institute of MIT and Harvard has generated one of the first comprehensive maps of cell types in a mammalian brain using recently developed technology called spatial transcriptomics, which ...
Dec 13, 2023
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A comprehensive study that integrates multiple analytic approaches has linked a regulatory gene network and functional defects in insulin-producing pancreatic beta cells to type 2 diabetes. The study, published Nov. 8 in ...
Nov 8, 2023
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Researchers have shown in a mouse model and lab cultures that a compound derived from hops reduces the abundance of a gut bacterium associated with metabolic syndrome.
Sep 21, 2023
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Researchers from the Complexity Science Hub (CSH) and the Medical University of Vienna (MedUni) have demonstrated for the first time that high doses of cholesterol-lowering statins impair bone quality in mice. The finding ...
Dec 19, 2022
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In the brain of adult mammals, neural stem cells ensure that new nerve cells (neurons), are constantly formed. This process, known as adult neurogenesis, helps mice maintain their sense of smell. A research team led by Dr. ...
Oct 5, 2022
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Maternal obesity impairs heart health and function of the fetus according to a new study in mice. The study, published in The Journal of Physiology found that maternal obesity causes molecular changes in the heart of the ...
May 12, 2022
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University of Maryland School of Medicine (UMSOM) researchers, working with scientists from the Regeneron Genetics Center (RGC), discovered a new gene variant associated with lower levels of heart-damaging LDL cholesterol ...
Dec 2, 2021
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Osteogenesis imperfecta (OI) is the most common genetic form of brittle bone disease and results in defects of both bone and connective tissue. OI patients can have significant problems with mobility due to joint dysfunction ...
Jun 14, 2021
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Diabetes, obesity and nonalcoholic fatty liver disease (NAFLD) are all common diseases that can lead to serious health implications. NAFLD affects over 30% of Americans, and is characterized as a fatty liver, which can progress ...
Jul 31, 2020
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