As humans age, hematopoietic stem cells—the immature precursor cells that give rise to all blood and immune cells—accumulate mutations. Some of the mutations allow these stem cells to self-renew and expand more effectively ...
Jun 5, 2024
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A team of scientists at the Broad Institute of MIT and Harvard has generated one of the first comprehensive maps of cell types in a mammalian brain using recently developed technology called spatial transcriptomics, which ...
Dec 13, 2023
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A comprehensive study that integrates multiple analytic approaches has linked a regulatory gene network and functional defects in insulin-producing pancreatic beta cells to type 2 diabetes. The study, published Nov. 8 in ...
Nov 8, 2023
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In the brain of adult mammals, neural stem cells ensure that new nerve cells (neurons), are constantly formed. This process, known as adult neurogenesis, helps mice maintain their sense of smell. A research team led by Dr. ...
Oct 5, 2022
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69
Osteogenesis imperfecta (OI) is the most common genetic form of brittle bone disease and results in defects of both bone and connective tissue. OI patients can have significant problems with mobility due to joint dysfunction ...
Jun 14, 2021
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Scientists at Johns Hopkins Medicine have found types of cells in the brain that are most susceptible to inherited genetic variants linked to schizophrenia. As a result, their work reveals a shortlist of the variants that ...
Jul 3, 2020
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150
When a mosquito infected with Zika virus bites someone, the skin is the first line of defense against infection.
Apr 3, 2020
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134
Obesity promotes the virulence of the influenza virus, according to a study conducted in mice published in mBio, an open-access journal of the American Society for Microbiology. The finding could explain, in part, why the ...
Mar 3, 2020
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126
The relay station of the brain, the substantia nigra, consists of different types of nerve cells and is responsible for controlling the execution of movements. Researchers at the University of Basel's Biozentrum have now ...
May 15, 2019
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Researchers have generated a cellular atlas of the mouse brain, based on the gene expression profiles of nearly 700,000 individual cells covering nine major brain regions.
Aug 10, 2018
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