As humans age, hematopoietic stem cells—the immature precursor cells that give rise to all blood and immune cells—accumulate mutations. Some of the mutations allow these stem cells to self-renew and expand more effectively ...
Jun 5, 2024
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Phenotypic plasticity is a cancer hallmark, and lung adeno-to-squamous transition (AST) triggered by LKB1 inactivation is significantly associated with drug resistance. Clinical data show that squamous transition occurs in ...
Jun 5, 2024
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An international study, published in Nature Communications, may facilitate the creation of new personalized treatments for people diagnosed with schizophrenia. These are patients who suffer from various types of symptoms, ...
May 30, 2024
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Researchers from Tokyo Medical and Dental University (TMDU) have found that donor keratinocytes injected into mouse embryos form sheets of epidermis that can be used as autologous skin grafts.
May 29, 2024
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A new study shows that hyperandrogenism—a key characteristic of polycystic ovary syndrome (PCOS)—affects immune cell populations in reproductive, metabolic and immunological tissues in a PCOS-like mouse model.
May 27, 2024
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The world's population has increased by more than 2.6-fold in the last 60 years. The growing trend continues—projections indicate that the number of people living on our planet will grow to 9 billion by 2037 from 8 billion ...
May 23, 2024
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The immune system strikes a fine balance by identifying and neutralizing disease-causing agents while carefully avoiding destruction of healthy tissues and cells. Now, researchers from Japan have shed new light on one of ...
May 20, 2024
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A new microporous scaffold functions as a minimally-invasive surveillance method to identify rejection prior to graft injury in a mouse model, according to a study published in Science Advances.
May 17, 2024
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In what they believe is a solution to a 30-year biological mystery, neuroscientists at Johns Hopkins Medicine say they have used genetically engineered mice to address how one mutation in the gene for the light-sensing protein ...
May 16, 2024
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When the heart is injured, as in a myocardial infarction, the damaged heart muscle cannot regenerate—instead, scar tissue forms. Cardiomyocytes, the heart muscle cells that generate contractile force, are lost for good. ...
May 16, 2024
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