Medical research

CRISPR halts Duchenne muscular dystrophy progression in dogs

Scientists for the first time have used CRISPR gene editing to halt the progression of Duchenne muscular dystrophy (DMD) in a large mammal, according to a study by UT Southwestern that provides a strong indication that a ...

Immunology

Chemotherapy-induced diarrhea traced to immune cells

Some 50 to 80 percent of cancer patients taking powerful chemotherapy drugs develop diarrhea, which can be severe and in some cases life-threatening. Their problems occur when contractions in the smooth muscle lining the ...

Cardiology

New target for treating heart failure identified

Changes in cellular struts called microtubules (MT) can affect the stiffness of diseased human heart muscle cells, and reversing these modifications can lessen the stiffness and improve the beating strength of these cells ...

Medical research

Polarized cells give the heart its fully developed form

When it first starts to develop, the heart is a simple tube. Reporting in the journal Nature Communications, researchers at MDC have now described how it forms itself into a its characteristic S-shape and how the ventricles ...

Neuroscience

Leg exercise is critical to brain and nervous system health

Groundbreaking research shows that neurological health depends as much on signals sent by the body's large, leg muscles to the brain as it does on directives from the brain to the muscles. Published today in Frontiers in ...

Cardiology

The secret to building a strong heart—blood vessels

Every year, a small but not insignificant number of babies are born with hearts whose muscles are spongy and thin, although exactly what causes that condition isn't clear. Now, Stanford biologists think they may have found ...

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