Individual cells within the same heart cope differently with high blood pressure, according to a study in human cells and mice by a team of cardiologists and computational biologists at the University of Tokyo. This is the ...
Oct 30, 2018
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Children in Rochester were recently among the first in the nation to receive an experimental treatment for Duchenne muscular dystrophy (DMD). The study is part of an accelerating trend of clinical trials involving gene therapies ...
Feb 10, 2022
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An innovative tool for the targeted modification of gene activity in heart muscle cells could establish itself as a standard method for research into cardiovascular diseases.
May 14, 2024
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Researchers led by the Francis Crick Institute have developed a zebrafish model of a human disease - Hirschsprung disease - that enables them to study the disease's causes and consequences in living animals and will help ...
Jan 12, 2017
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Wataru Kimura and colleagues at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan have discovered how the hearts of newborn marsupials retain the ability to regenerate for several weeks. Using this knowledge, ...
Aug 22, 2022
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Up to 8 percent of people from India, Pakistan, Bangladesh and other South Asian countries carry a mutated gene that causes heart failure and potentially fatal heart attacks.
Jan 15, 2015
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New research on two promising gene therapies suggests that combining them into one treatment not only repairs muscle damage caused by Duchenne muscular dystrophy, but also prevents future injury from the muscle-wasting disease. ...
Aug 9, 2013
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In response to conditions such as high blood pressure and reduced blood flow to cardiac muscle, the adult heart can drastically enlarge, a process called pathological hypertrophy that preserves cardiac function in the short ...
Jan 30, 2019
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A new research paper titled "AAV1.NT-3 gene therapy prevents age-related sarcopenia" has been published in Aging.
Mar 15, 2023
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Progress by a UMass Chan Medical School researcher in developing a gene therapy for a rare, crippling bone disease has reached an important milestone with demonstration of proof-of-concept in a humanized mouse model of fibrodysplasia ...
Oct 20, 2022
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