Oncology & Cancer

Armoring anti-cancer T cells against immunosuppressants

Duke-NUS Medical School researchers, together with collaborators in Singapore, have designed armored immune cells that can attack recurring cancer in liver transplant patients, while temporarily evading immunosuppressant ...

Diseases, Conditions, Syndromes

Risk factors identified for autoimmune hepatitis after liver transplant

A multicenter study performed by a large international consortium that includes UT Southwestern has outlined a set of risk factors and outcomes for patients with autoimmune hepatitis (AIH) that recurs after liver transplantation. ...

Medications

Maintenance immunosuppressive drugs tied to severe COVID-19

Maintenance immunosuppressive drugs are associated with an increased risk for COVID-19 hospitalization in solid organ transplant recipients, according to a study published online Nov. 7 in JAMA Network Open.

Diseases, Conditions, Syndromes

A nanogel-based treatment for lupus

Systemic lupus erythematosus (SLE) is disease in which the immune system mistakenly attacks healthy tissues, resulting in inflammation and tissue damage. Current treatments are focused on suppression of the immune system, ...

Immunology

Use of stem cells, conditioning induces immune tolerance

(HealthDay) -- A novel approach using a bioengineered mobilized cellular product enriched with hematopoietic stem cells (HSCs) and tolerogenic graft facilitating cells (FCs) in combination with nonmyeloablative conditioning ...

Medications

Mycophenolate mofetil treats immune thrombocytopenia

(HealthDay)—For adults with immune thrombocytopenia, the addition of mycophenolate mofetil to a glucocorticoid for first-line treatment is associated with fewer treatment failures and higher response rates than glucocorticoid-only ...

Medications

Recommendations developed for atopic dermatitis therapies

In updated guidelines issued by the American Academy of Dermatology and published online Nov. 7 in the Journal of the American Academy of Dermatology, recommendations are presented for use of phototherapy and systemic therapies ...

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