Although it has long been recognized that mutations of gene NPM1 play an important role in acute myeloid leukemia, no one has determined how the normal and the mutated forms of the protein NPM1 function.
Nov 13, 2018
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8
Using freshly resected lung tissue from 21 patients and two distinct mouse models, tuberculosis researchers at the University of Alabama at Birmingham and the Africa Health Research Institute, or AHRI, have identified a protein ...
Nov 13, 2018
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28
Think of energy metabolism like a party popper: Ripping something apart releases a bang. Most of your cells rip apart sugar to release the "bang" of energy. Sometimes they rip apart fats, and in a pinch, cells can even metabolize ...
Nov 12, 2018
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1201
Scientists at the University of Birmingham have revealed the roles that different types of gene mutations play in causing blood cancers in a study that was the culmination of a decade's research.
Nov 12, 2018
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78
B cells are important in helping the immune system fight pathogens. However, in the case of the neurological autoimmune disease multiple sclerosis (MS), they can damage nerve tissue. When particular control cells are missing, ...
Nov 9, 2018
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87
A combination of the standard-of-care chemotherapy drug known as azacitidine, with nivolumab, an immune checkpoint inhibitor, demonstrated an encouraging response rate and overall survival in patients with relapsed or refractory ...
Nov 8, 2018
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0
Mount Sinai researchers have developed a novel type of immunotherapy based on innovative nanotechnology that induces long-term organ transplant acceptance in mice. Their study, published in the November 6 online issue of ...
Nov 6, 2018
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4
Scientists are hoping to develop a new generation of therapies to tackle acute myeloid leukaemia, a type of blood cancer which is particularly difficult to treat.
Nov 6, 2018
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1
Researchers led by a UCLA bioengineer have developed a therapy—based on two types of cells joined into a single unit—that could help strengthen existing treatments for acute myeloid leukemia. One of the cells is a blood ...
Oct 30, 2018
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118
Researchers from The Ottawa Hospital and the University of Ottawa have developed a promising targeted strategy to treat chemotherapy-resistant acute myeloid leukemia (AML) and a diagnostic test to determine which AML patients ...
Oct 22, 2018
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22
