Neuroscience

Gene therapy opens new possibilities for treating chronic pain

Researchers from the Nuffield Department of Clinical Neurosciences at the University of Oxford, along with colleagues at Cambridge University and Barts and the London School of Medicine and Dentistry, have shown the potential ...

Genetics

Gene therapy treats chronic pain by dialing down sodium

Researchers at NYU College of Dentistry's Pain Research Center have developed a gene therapy that treats chronic pain by indirectly regulating a specific sodium ion channel, according to a new study published in the Proceedings ...

Medical research

New therapeutic target for osteoarthritis identified

Investigators have discovered that a subset of sensory neurons promote osteoarthritis-related joint pain and inflammation, suggesting a new therapeutic target for pain management, according to findings published in Nature ...

Neuroscience

Clues to the cause of chronic gut pain

New insights into chronic gut pain offer hope for improved treatments for irritable bowel syndrome and anxiety treatment.

Medical research

Wearable microscopes advance spinal cord imaging in mice

The spinal cord acts as a messenger, carrying signals between the brain and body to regulate everything from breathing to movement. While the spinal cord is known to play an essential role in relaying pain signals, technology ...

Neuroscience

Calcium channels regulate neuroinflammation and neuropathic pain

Northwestern Medicine investigators have discovered that specific calcium channels help regulate sex differences in the functioning of immune cells for neuroinflammation and overall neuropathic pain, according to findings ...

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