Immunology

Chemotherapy-induced diarrhea traced to immune cells

Some 50 to 80 percent of cancer patients taking powerful chemotherapy drugs develop diarrhea, which can be severe and in some cases life-threatening. Their problems occur when contractions in the smooth muscle lining the ...

Neuroscience

Non-opioid drug relieves pain in mice, targets immune cells

Faced with the epidemic of opioid addiction, researchers have been charged with finding other strategies to treat pain. Their efforts largely have focused on nerve cells that transmit pain signals to the spinal cord and brain. ...

Medical research

Slim down by targeting the hormone uroguanylin

The number of people who are obese and suffer one or more of its associated health problems (including type 2 diabetes) is escalating dramatically. Researchers are seeking to identify new targets for therapeutics that could ...

Neuroscience

Nerve cell protection free from side effects

The hormone erythropoietin (Epo) is a well-known doping substance that has a long history of abuse in endurance sports such as cycling. In addition to promoting red blood cell production (erythropoiesis), which improves the ...

Alzheimer's disease & dementia

Alzheimer's: Nicotinic receptors as a new therapeutic target

Several scientific studies have indicated that nicotine may be beneficial for memory function. Scientists from the Institut Pasteur and the CNRS set out to shed further light on the properties attributed to nicotine - which ...

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