Parkinson's & Movement disorders

Potential drug lessens neurodegeneration in Parkinson's disease model

The first test in a mammalian model of a potential new class of drugs to treat Parkinson's disease shows abatement of neurodegeneration in the brains of test rats and no significant toxicities, University of Alabama at Birmingham ...

Alzheimer's disease & dementia

ApoE4 Alzheimer's gene causes brain's blood vessels to leak, die

Common variants of the ApoE gene are strongly associated with the risk of developing late-onset Alzheimer's disease, but the gene's role in the disease has been unclear. Now, researchers funded by the National Institutes ...

Medical research

Identification of bacterial proteins that promote neurodegeneration

Growing evidence indicates that gut microbiota plays a critical role in regulating the progression of neurodegenerative diseases such as Parkinson's disease (PD) and Alzheimer's disease (AD), but the molecular mechanism underlying ...

Medical research

New role for blood-brain barrier in neuron function and damage

While the role of the blood-brain barrier has long been appreciated for its ability to maintain precise control over what molecules can enter the nervous system, very little is known about how the cells that form the barrier ...

Neuroscience

Researchers map brain cell changes in Alzheimer's disease

A common sign of Alzheimer's disease is the excessive buildup of two types of protein in the brain: tangles of tau proteins that accumulate inside cells, and amyloid-β proteins that form plaques outside the cells. Researchers ...

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