Early disease stages of multiple sclerosis (MS) are primarily characterized by immune cell infiltration of the central nervous system (CNS). This causes inflammation that damages the myelin sheaths that insulate nerves, which ...
Jun 28, 2019
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Just like pruning a tree helps promote proper growth, the brain uses synaptic pruning to get rid of unnecessary connections between its cells. However, when this normal process, which occurs between early childhood and adulthood, ...
Mar 23, 2023
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Choline, an essential nutrient produced in small amounts in the liver and found in foods including eggs, broccoli, beans, meat and poultry, is a vital ingredient for human health. A new study explores how a deficiency of ...
Jan 17, 2023
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New research at Oregon State University provides evidence for the first time that disruption of circadian rhythms – the biological "clocks" found in many animals – can clearly cause accelerated neurodegeneration, ...
Jan 10, 2012
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Technology developed by researchers at The University of Texas at Austin could significantly reduce the time and cost to finding a cure for Alzheimer's disease and help answer one of the greatest biological questions: why ...
Oct 17, 2011
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People who eat a healthy diet during middle age have a larger brain volume than those with less healthy diets, new research reveals, suggesting food choices in midlife may reduce the risk of dementia and other degenerative ...
Dec 15, 2021
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The first test in a mammalian model of a potential new class of drugs to treat Parkinson's disease shows abatement of neurodegeneration in the brains of test rats and no significant toxicities, University of Alabama at Birmingham ...
Jun 26, 2015
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Researchers at the Complutense University of Madrid (UCM) have identified changes in retinal layer thickness, inflammation or thinning in patients with mild Alzheimer's disease, confirming that the retina is one of the most ...
Sep 13, 2019
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Common variants of the ApoE gene are strongly associated with the risk of developing late-onset Alzheimer's disease, but the gene's role in the disease has been unclear. Now, researchers funded by the National Institutes ...
May 16, 2012
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Growing evidence indicates that gut microbiota plays a critical role in regulating the progression of neurodegenerative diseases such as Parkinson's disease (PD) and Alzheimer's disease (AD), but the molecular mechanism underlying ...
Sep 7, 2021
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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons. Many neurodegenerative diseases including Parkinson’s, Alzheimer’s, and Huntington’s occur as a result of neurodegenerative processes. As research progresses, many similarities appear which relate these diseases to one another on a sub-cellular level. Discovering these similarities offers hope for therapeutic advances that could ameliorate many diseases simultaneously. There are many parallels between different neurodegenerative disorders including atypical protein assemblies as well as induced cell death. Neurodegeneration can be found in many different levels of neuronal circuitry ranging from molecular to systemic.
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