While the role of the blood-brain barrier has long been appreciated for its ability to maintain precise control over what molecules can enter the nervous system, very little is known about how the cells that form the barrier ...
Aug 15, 2022
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(Medical Xpress)—When the brains of those who have succumbed to age-related neurodegeneration are analyzed post-mortem, they typically show significant atrophy on all scales. Not only is the cortex thinner and sparser, ...
(Medical Xpress) -- Mayo Clinic researchers have discovered two mutations responsible for a devastating neurological condition they first identified 15 years ago. The researchers say their study -- appearing in Nature Genetics ...
May 1, 2011
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Although there are still some aspects pending confirmation for its use in the clinical setting, and its resolution needs to be improved slightly, a study by the UPV/EHU and Biobizkaia has shown that a method routinely used ...
Apr 19, 2024
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Neurodegeneration, or the gradual loss of neuron function, is one of the key features of Alzheimer's disease. However, it doesn't affect all parts of the brain equally.
Apr 19, 2023
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Just like pruning a tree helps promote proper growth, the brain uses synaptic pruning to get rid of unnecessary connections between its cells. However, when this normal process, which occurs between early childhood and adulthood, ...
Mar 23, 2023
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Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage ...
Mar 8, 2023
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In a study published in Proceedings of the National Academy of Sciences, a research team led by Dr. Zhou Jiawei at the Institute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology of the Chinese ...
Feb 20, 2023
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A common sign of Alzheimer's disease is the excessive buildup of two types of protein in the brain: tangles of tau proteins that accumulate inside cells, and amyloid-β proteins that form plaques outside the cells. Researchers ...
Feb 2, 2023
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Choline, an essential nutrient produced in small amounts in the liver and found in foods including eggs, broccoli, beans, meat and poultry, is a vital ingredient for human health. A new study explores how a deficiency of ...
Jan 17, 2023
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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons. Many neurodegenerative diseases including Parkinson’s, Alzheimer’s, and Huntington’s occur as a result of neurodegenerative processes. As research progresses, many similarities appear which relate these diseases to one another on a sub-cellular level. Discovering these similarities offers hope for therapeutic advances that could ameliorate many diseases simultaneously. There are many parallels between different neurodegenerative disorders including atypical protein assemblies as well as induced cell death. Neurodegeneration can be found in many different levels of neuronal circuitry ranging from molecular to systemic.
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