Neuroscience

Probe detects the destruction of defective mitochondria

A versatile probe that can detect with pinpoint accuracy the programmed destruction of defective mitochondria—the powerhouses of cells—has been developed by RIKEN researchers. They used it to show that damaged mitochondria ...

Medical research

Newly discovered mechanism can explain increased risk of dementia

Millions of people around the world use proton pump inhibitors for conditions like heartburn, gastritis and stomach ulcers. Researchers at Karolinska Institutet in Sweden now report that the long-term use of these drugs could ...

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Neurotransmitter

Neurotransmitters are endogenous chemicals which relay, amplify, and modulate signals between a neuron and another cell. Neurotransmitters are packaged into synaptic vesicles that cluster beneath the membrane on the presynaptic side of a synapse, and are released into the synaptic cleft, where they bind to receptors in the membrane on the postsynaptic side of the synapse. Release of neurotransmitters usually follows arrival of an action potential at the synapse, but may follow graded electrical potentials. Low level "baseline" release also occurs without electrical stimulation.

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