After Alzheimer's, Parkinson's is the most common neurodegenerative disease in the world. More than six million people worldwide suffer from it. In this disease, alpha-synuclein proteins form thread-like structures called ...
Nov 15, 2022
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980
Revealing zinc's interaction with a critical transport protein underscores the need to study biological pathways under physiologically relevant conditions.
Oct 17, 2022
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25
Wear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis. Scientists at UF Scripps Biomedical Research have found a possible new target to fight this painful cascade.
Oct 14, 2022
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281
Prof. Liu Guanghui and his colleagues from the Institute of Zoology and the Beijing Institute of Genomics of the Chinese Academy of Sciences have collaborated to find that Apolipoprotein E (APOE) destabilizes heterochromatin ...
Apr 7, 2022
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30
The Src protein takes part in the regulation of many physiological processes such as the survival, migration or cell adhesion as a response to stimuli received from several receptors of the membrane. Although it is demonstrated ...
Jan 12, 2022
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1
Adenoviruses have a linchpin protein that stabilizes their DNA until it reaches the infected cell's nucleus. The protein then detaches from the viral genome, and the virus uncoats. Only then are the genes released into the ...
Dec 21, 2021
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324
The nuclear envelope (NE) is composed of the outer nuclear membrane (ONM) and the inner nuclear membrane (INM), which are separated by the perinuclear space and joined at nuclear pore complexes. INM proteins play crucial ...
Dec 8, 2021
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49
Each day the average human heart beats 100,000 times and pumps about 2,000 gallons of blood. It's a process that is critical to life, and yet it often goes awry for unknown reasons.
Jun 24, 2021
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13
Immunomodulatory drugs, including the Contergan derivatives lenalidomide and pomalidomide, have significantly improved the therapy of hematologic malignancies such as multiple myeloma. Researchers at the Technical University ...
Feb 12, 2021
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44
Researchers have long sought to explain precisely how the most common genetic mutation linked to both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia causes the death of nerve cells. Now, Johns Hopkins Medicine ...
Sep 3, 2020
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