Revealing zinc's interaction with a critical transport protein underscores the need to study biological pathways under physiologically relevant conditions.
Oct 17, 2022
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25
Prof. Liu Guanghui and his colleagues from the Institute of Zoology and the Beijing Institute of Genomics of the Chinese Academy of Sciences have collaborated to find that Apolipoprotein E (APOE) destabilizes heterochromatin ...
Apr 7, 2022
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30
The Src protein takes part in the regulation of many physiological processes such as the survival, migration or cell adhesion as a response to stimuli received from several receptors of the membrane. Although it is demonstrated ...
Jan 12, 2022
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1
The nuclear envelope (NE) is composed of the outer nuclear membrane (ONM) and the inner nuclear membrane (INM), which are separated by the perinuclear space and joined at nuclear pore complexes. INM proteins play crucial ...
Dec 8, 2021
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49
Immunomodulatory drugs, including the Contergan derivatives lenalidomide and pomalidomide, have significantly improved the therapy of hematologic malignancies such as multiple myeloma. Researchers at the Technical University ...
Feb 12, 2021
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44
Lung cancer is the predominant cause of cancer related deaths. Within the main types of lung cancers, small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), NSCLC accounts for approximately 85%, with a poor ...
Mar 16, 2020
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1
Many, but not all, proteins in a living cell have a defined three-dimensional structure. The interrelationship between the structure and function of proteins is the focus of many research initiatives that extend to the development ...
Jul 29, 2019
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59
Radioactive antibodies that target cancer cells are used for medical diagnostics with PET imaging or for targeted radioimmunotherapy. Researchers from the University of Zurich have created a new method for radiolabelling ...
Apr 24, 2019
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1
The absence of one copy of a single gene in the brain causes a rare, as-yet-unnamed neurological disorder, according to new research that builds on decades of work by a University at Buffalo biochemist and his colleagues.
Nov 13, 2018
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21
The largest known protein, titin, named for the Titan giants of Greek mythology, is a molecular spring found in cardiac muscle. It provides structural support and maintains tension during muscle stretching. Mutations in the ...
Jun 28, 2018
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