Diseases, Conditions, Syndromes

First rapid tests for chlamydia, gonorrhea exhibit 100% sensitivity

More than half of the estimated 374 million new sexually transmitted infections (STIs) in 2020 were either chlamydia or gonorrhea, which are often asymptomatic and co-occurring, according to the World Health Organization. ...

Oncology & Cancer

New insights into melanoma development and therapy

Malignant melanoma is a type of skin cancer that originates from melanocytes or nevi, causing about 80% of skin cancer-related deaths. While some cases have shown significant response to existing molecular targeted therapies, ...

Endocrinology & Metabolism

Metabolism meets signaling to fine-tune cell growth

Cells use a variety of metabolic pathways to synthesize the building blocks for growth and proliferation. To ensure balanced growth, these biosynthetic processes must be tightly coordinated. Researchers from the Max Planck ...

Diseases, Conditions, Syndromes

Know your status: The importance of HIV testing

It's not making major news headlines like in the '80s, but HIV remains a significant health concern. About 38 million people are living with HIV, the virus that causes AIDS, according to the World Health Organization.

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Nucleic acid

A nucleic acid is a macromolecule composed of chains of monomeric nucleotides. In biochemistry these molecules carry genetic information or form structures within cells. The most common nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Nucleic acids are universal in living things, as they are found in all cells and viruses. Nucleic acids were first discovered by Friedrich Miescher in 1871.

Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally-occurring DNA or RNA by changes to the backbone of the molecule.

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