Diseases, Conditions, Syndromes

SARS-CoV-2 detection in 30 minutes using gene scissors

CRISPR-Cas is versatile: Besides the controversial genetically modified organisms (GMOs), created through gene editing, various new scientific studies use different orthologues of the effector protein Cas to detect nucleic ...

Diseases, Conditions, Syndromes

Advancing the state of the art in neutralizing stronger COVID-19 variants

The emergence of unpredictable variants and their stronger infectivity make the COVID-19 pandemic never-ending—over 300 omicron variants have been reported so far. Will there ever be a universal cure for COVID-19 that neutralizes ...

Medical research

Promotion of cancer progression via extracellular vesicles

The advent of cell phones, the internet, and various messaging platforms has allowed for faster and broader communication worldwide. But did you know that your body has its own complex communication system in the form of ...

Oncology & Cancer

New technique adds to the expanding suite of TAPS capabilities

In a new paper published in Nucleic Acids Research, a team led by Ludwig Oxford's Chunxiao Song reported a method for whole-genome long-read sequencing using TAPS (for Tet-assisted pyridine borane sequencing), the method ...

Medical research

Speeding up the search for the next COVID-19 antiviral

To put the COVID-19 pandemic in the rearview mirror and prevent other coronaviruses from causing havoc, the world needs an arsenal of measures to prevent and treat these infections. To develop new medications, researchers ...

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Nucleic acid

A nucleic acid is a macromolecule composed of chains of monomeric nucleotides. In biochemistry these molecules carry genetic information or form structures within cells. The most common nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Nucleic acids are universal in living things, as they are found in all cells and viruses. Nucleic acids were first discovered by Friedrich Miescher in 1871.

Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally-occurring DNA or RNA by changes to the backbone of the molecule.

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