Females are born with a finite number of eggs that are steadily depleted throughout their lifetime. This reserve of eggs is selected from a much larger pool of millions of precursor cells, or oocytes, that form during fetal ...
Sep 27, 2018
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A Monash University study has uncovered the role DNA repair plays in preserving egg quality, offering hope for women whose eggs may be damaged through treatments such as radiation and chemotherapy.
May 22, 2020
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Excessive body fat is associated with negative effects on female fertility and pregnancy. In mice, maternal obesity impairs proper development of egg precursor cells called oocytes. In a recent paper published in Molecular ...
Aug 16, 2018
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A compelling new genetic study tracing the origins of immature egg cells, or 'oocytes', from the embryonic period throughout adulthood adds new information to a growing controversy. The notion of a "biological clock" in women ...
Jul 26, 2012
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(Medical Xpress)—Scientists supported by the National Institutes of Health have a new theory as to why a woman's fertility declines after her mid-30s. They also suggest an approach that might help slow the process, enhancing ...
May 22, 2013
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Researchers led by Kyushu University have succeeded in using mouse stem cells to reconstruct structures in the ovarian environment critical for the generation of mature egg cells. Moreover, they were able to apply their findings ...
Sep 14, 2021
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More than 7% of human oocytes contain at least one exchangeless chromosome pair, demonstrating a remarkably high level of meiotic recombination failure, finds a study appearing December 10 in the American Journal of Human ...
Dec 10, 2020
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Researchers at Universitat Autonoma de Barcelona analysed the effects of Bisphenol A (BPA), a polymer widely used to manufacture plastics, in an in vitro culture of ovaries. The research demonstrated that exposure to this ...
Sep 21, 2011
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Age may adversely affect women's fertility by impairing levels of RNA molecules which in turn alter the function of genes involved in key biological pathways during the final maturation stage of a human egg cell, according ...
Apr 28, 2021
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Cancer treatment can rob childbearing-age women of fertility, but new research has uncloaked how the body's own traitor protein conspires with chemo and other harsh therapies against the ovaries' primordial follicles, home ...
