Medical research

New discovery helps researchers rethink organoid cultures

Organoids are stem cell-based tissue surrogates that can mimic the structure and function of organs, and they have become a key component of numerous types of medical research in recent years. But researchers from The University ...

Cardiology

Heart attack in a dish: a 3-D model

In the U.S., someone has a heart attack every 40 seconds, and yet researchers have not had a model that fully mimics what occurs in the human heart after a heart attack.

Medications

Brain organoids with the potential to predict drug permeability

The human brain is bathed in a supportive fluid called the cerebrospinal fluid (CSF) that provides nutrients and is required for proper brain function. The composition of human CSF and how it is made are poorly understood ...

Genetics

Probing the genes that organize early brain development

When brains begin developing, there are a lot of moving parts—and when mutations happen in early neurodevelopment, it can lead to disorders like macrocephaly and autism. But scientists don't know much about the ways that ...

Oncology & Cancer

Brain organoids reveal glioblastoma origins

Glioblastomas are the most aggressive form of brain cancer—they grow and spread rapidly through the brain and are virtually impossible to eradicate, typically leading to death within one or two years of diagnosis. Scientists ...

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