Oncology & Cancer

Cancer metastasis: The unexpected perils of hypoxia

The low oxygen concentrations that prevail in many tumors enhance their propensity to metastasize to other tissues. Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich led by Professor Heiko Hermeking have now ...

Medical research

Study signals need to screen genes for stem cell transplants

Regenerative medicine using human pluripotent stem cells to grow transplantable tissue outside the body carries the promise to treat a range of intractable disorders, such as diabetes and Parkinson's disease.

Diseases, Conditions, Syndromes

p53 critical to recovering from acetaminophen overdose

Results from a new study show that after an acetaminophen overdose the p53 protein plays a key role in preventing the progression of liver damage and signaling the liver to repair itself. The findings could lead to new treatments ...

Oncology & Cancer

New insight illuminates how cells respond to stress

Duke Cancer Institute scientists have described a previously unknown series of steps that cells undergo when stressed, adding crucial information to the understanding of DNA damage that is at the heart of research into aging ...

Oncology & Cancer

Study sheds light on dark side of tumor suppressor gene, p53

The gene p53 is the most commonly mutated gene in cancer - it is p53's job to monitor cells for DNA damage and to mark damaged cells for destruction and so cancer cells with mutated DNA must disable p53 before it disables ...

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