Neuroscience

Understanding pain exacerbation with opioid use

A new study published in JNeurosci advances understanding of how the potent opioid analgesic fentanyl can increase pain sensitivity in animals. These findings could inform the development of treatments for chronic pain that ...

Neuroscience

Why head and face pain causes more suffering

Hate headaches? The distress you feel is not all in your—well, head. People consistently rate pain of the head, face, eyeballs, ears and teeth as more disruptive, and more emotionally draining, than pain elsewhere in the ...

Neuroscience

Unexpected mechanism behind chronic nerve pain

It has long been assumed that chronic nerve pain is caused by hypersensitivity in the neurons that transmit pain. Researchers at Karolinska Institutet in Sweden now show that another kind of neuron that normally allows us ...

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