In a first-of-its-kind effort to illuminate the biochemical impact of trauma, researchers at NYU Langone Medical Center have discovered a connection between the quantity of cannabinoid receptors in the human brain, known ...
May 14, 2013
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Opioid drugs are the most widely prescribed and effective type of pain medication. But they are highly addictive and have some unpleasant and potentially deadly side effects.
Dec 5, 2017
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Scientists at Scripps Research in Florida have created a collection of new pain-relieving compounds, that like morphine and other drugs, provide relief via activation of opioid receptors, but without inducing many dangerous ...
Nov 22, 2021
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A drug targeting a protein complex containing two different types of opioid receptors may be an effective alternative to morphine and other opioid pain medications, without any of the side effects or risk of dependence, according ...
Jul 15, 2013
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A team of researchers at Johns Hopkins have found that activating nerve cell receptors along two chemical pathways—one that has previously been linked to how the brain senses "itch"—may improve pain relief when combined ...
Jun 25, 2018
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When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, ...
Feb 10, 2021
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Fast communication between our brain cells—or neurotransmission as it is called—is hugely important for our brain to work properly. Some of the messengers involved in this form of communication are neuropeptides, which ...
Mar 31, 2020
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OHSU research suggests an avenue for developing treatments for chronic pain that harness the medicinal properties of cannabis while minimizing the threat of addiction.
Jan 12, 2017
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The discovery of a gene for migraine holds great promise in the quest for new approaches -- possibly even a pill -- for preventing the disease, says a panel of experts presenting data at the annual scientific meeting of the ...
Jun 1, 2011
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At the cellular level, pain and pain relief are caused by two different signaling pathways. But the two pathways aren't necessarily independent of one another, according to a study published by Carnegie Mellon researchers ...
Apr 13, 2015
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