A method to prevent the body from developing tolerance to morphine, a powerful and commonly used pain medication, has been discovered by a Georgia State University researcher.
Oct 4, 2013
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New research published in BioMed Central's open access journal BMC Medicine reassessing clinical data from trials, which investigate ways of treating side effects of therapy for prostate cancer, finds that tamoxifen, an anti-estrogen ...
Aug 27, 2012
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Scripps Research scientists have found that LY2444296—a compound that selectively blocks the kappa opioid receptor (KOP)—may reduce drinking in cases of alcohol dependence in animal studies. The findings, which were published ...
Mar 29, 2024
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For patients managing cancer and other chronic health issues, painkillers such as morphine and Vicodin are often essential for pain relief. The body's natural tendency to develop tolerance to these medications, however, often ...
Jun 10, 2013
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Opioids regulate the feelings of pleasure and pain in the brain. A study by the national Turku PET Centre in Finland shows that age, sex and smoking influence μ-opioid receptor density in the brain. The results of the study ...
May 28, 2020
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Researchers at the University of Granada led a novel study in mice that shows that sigma‑1 receptor blockers cause white blood cells or leukocytes to relieve pain when a tissue is inflamed
Feb 5, 2018
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Researchers at Karolinska Institutet, in collaboration with JLP Health and others, have identified how the tick-borne Crimean-Congo hemorrhagic fever virus enters our cells. The results are published in Nature Microbiology ...
Mar 28, 2024
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Researchers from KU Leuven, Belgium, have identified the cause of abdominal pain in patients with irritable bowel syndrome (IBS). As a result, they were able to select a medicine that could reduce or end that pain. This medicine ...
Jan 14, 2016
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Researchers have shown that pain-induced changes in the rat brain's opioid receptor system may explain the limited effectiveness of opioid therapy in chronic pain and may play a role in the depression that often accompanies ...
May 25, 2018
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(Medical Xpress)—Researchers at the School of Medicine have identified a subset of nerve cells that mediates a form of chronic, touch-evoked pain called tactile allodynia, a condition that is resistant to conventional pain ...
Mar 10, 2014
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