A drug used to target IDH1 mutations in select cancers also appears to inhibit the wild-type form of the enzyme, under certain conditions. This feature explains why a large group of different cancers are vulnerable to the ...
Jun 9, 2022
0
64
Before a patient can undergo T cell therapy designed to target cancerous tumors, the patient's entire immune system must be destroyed with chemotherapy or radiation. The toxic side effects are well known, including nausea, ...
Jun 8, 2022
0
89
Aerobic exercise reprograms the immune system to reduce pancreatic tumor growth and amplify the effects of immunotherapy, a new study finds.
Jun 2, 2022
0
113
Researchers at Washington University School of Medicine in St. Louis have developed a way to attack synovial sarcoma—a rare tumor of soft tissues, such as ligaments and muscles—using an investigational drug that triggers ...
May 31, 2022
0
66
Pancreatic cancers recycle resources to fuel their survival and growth, opening up the possibility of new treatments aimed at stopping them from doing so, scientists report.
May 6, 2022
0
65
Scar-like cells that make up a sizable portion of malignant pancreatic tumors and shield these cancers from immune attack are derived from mesothelial cells that line tissues and organs, a new study led by UT Southwestern ...
May 5, 2022
0
63
Every day, your pancreas produces about one cup of digestive juices, a mixture of molecules that can break down the food you eat. But if these powerful molecules become activated before they make their way to the gut, they ...
Apr 21, 2022
0
8
The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously—a phenomenon known as hyperglycemia—thus triggering diabetes. After discovering ...
Apr 19, 2022
0
51
Scientists at Nanyang Technological University, Singapore's (NTU Singapore) Lee Kong Chian School of Medicine (LKCMedicine) have mapped a novel cellular pathway that shows that saturated fat contributes to the development ...
Apr 18, 2022
0
127
Investigators at the University of Miami Miller School of Medicine have designed RNA molecules that home to human pancreatic beta cells, the cells that produce insulin and are destroyed in patients with type 1 and type 2 ...
Apr 7, 2022
0
46
