Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins. KRAS, for example, normally acts as an on/off switch for cellular proliferation, but mutations ...
May 11, 2023
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A large team of medical researchers at Memorial Sloan Kettering Cancer Center, in New York, working with colleagues from the Icahn School of Medicine at Mount Sinai and German firm BioNTech has developed a personalized mRNA ...
Pancreatic cancer drug response and resistance has been uncovered in unprecedented detail, thanks to a research tool developed at the Garvan Institute.
Apr 28, 2023
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A unique treatment combining radiation and immunotherapy can eradicate pancreatic tumors while stopping the cancer from spreading, according to a new study by researchers at the University of Colorado Cancer Center.
Apr 27, 2023
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Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer. It's also one of the deadliest. More than 90% of PDAC patients die within five years of diagnosis. Usually, by the time the cancer is identified, ...
Apr 26, 2023
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Pancreatic cancers are deadly and hard to treat, in part because they are so often detected at an advanced stage; overall five-year survival rates are about 11%. Two separate labs at Boston Children's Hospital took out-of-the-box ...
Apr 25, 2023
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Researchers at the Johns Hopkins Kimmel Cancer Center identified a novel cell signaling pathway that potentially could be targeted in therapy for patients with aggressive pancreatic cancers.
Apr 24, 2023
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Much of the research on new cancer treatments in the last two decades has focused on genetic targets that allow cancers to grow and spread by altering cell signaling or shutting off tumor suppressors. There is a growing body ...
Apr 7, 2023
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A new research paper, titled "VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer," was published in Genes & Cancer on March ...
Mar 24, 2023
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Researchers have shown for the first time exactly how immature neutrophils—white blood cells that are an important part of the immune system—are hijacked by pancreatic cancers to drive immunosuppression and treatment ...
Mar 22, 2023
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