Nearly one-third of cases of Wilms tumor, a pediatric cancer of the kidney, are linked to a gene called Lin28, according to research from Boston Children's Hospital. Mice engineered to express Lin28 in their kidneys developed ...
Apr 13, 2014
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The WTX gene is mutated in approximately 30 percent of Wilms tumors, a pediatric kidney cancer. Like many genes, WTX is part of a family. In this case, WTX has two related siblings, FAM123A and FAM123C. While cancer researchers ...
Aug 30, 2012
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A new Journal of the Endocrine Society study highlights how to identify children at high risk of developing type 2 diabetes and strategies for prevention, such as anti-obesity or anti-diabetes medication and lifestyle changes.
Oct 12, 2023
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Northwestern Medicine investigators have discovered that the overexpression of a transcription factor prevented bone loss in mouse models of chronic kidney disease, according to a recent study published in the Journal of ...
Jun 5, 2023
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A longstanding approach to surgeries for children with kidney tumors has been an abundance of caution.
May 1, 2023
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Acute kidney injury occurs (AKI) in one out of four babies, children and young adults during an intensive care stay for any reason, and yet the condition is poorly understood. It is associated with various treatments or diagnostic ...
Sep 30, 2022
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Jaxon Green, 6, was diagnosed with kidney disease the day he was born. His illness meant that for years his life would depend on daily dialysis. And because his family lives in Tamaqua, a rural Pennsylvania town, his diagnosis ...
Aug 29, 2022
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In cancer, there's a mistake in the hereditary material, the DNA, which causes uncontrollable growth of cells in the body. One in ten children with cancer has hereditary predisposition: a combination of DNA changes, spontaneous ...
Mar 1, 2022
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The need for pediatric nephrologists to develop a special expertise in the onco-nephrology field is increasingly important as childhood cancer rates have been on the rise and new therapy protocols are advancing, according ...
Mar 3, 2021
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A new randomized trial examines the effect of automated clinical decision support on team evaluation of pediatric inpatients at high risk for acute kidney injury (AKI).
Oct 4, 2019
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