A topical gel that blocks the receptor for a metabolic byproduct called succinate treats gum disease by suppressing inflammation and changing the makeup of bacteria in the mouth, according to a new study led by researchers ...
Sep 20, 2022
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Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part ...
Dec 23, 2021
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In diseases characterized by bone loss -such as periodontitis, rheumatoid arthritis, and osteoporosis- there is a lot that scientists still don't understand. What is the role of the immune response in the process? What happens ...
Jan 11, 2021
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An unhealthy population of microbes in the mouth triggers specialized immune cells that inflame and destroy tissues, leading to the type of bone loss associated with a severe form of gum disease, according to a new study ...
Oct 17, 2018
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A new study led by University of Pennsylvania researchers has found that the oral microbiome is affected by diabetes, causing a shift to increase its pathogenicity. The research, published in the journal Cell Host & Microbe ...
Jul 12, 2017
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Periodontitis, a severe form of gum disease, doesn't just cause soft-tissue inflammation and bleeding. It also destroys the bone that supports the teeth. If it progresses unchecked, it can lead to tooth loss and is even associated ...
Sep 30, 2015
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Patients with leukocyte adhesion deficiency, or LAD, suffer from frequent bacterial infections, including the severe gum disease known as periodontitis. These patients often lose their teeth early in life.
Mar 26, 2014
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Bone loss is a part of aging that compromises quality of life and movement in many older people, but regenerative treatments to improve their health and well-being have been limited. Now, a study led by Lankenau Institute ...
Jan 19, 2023
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A visit to the dentist's office could provide a glimpse into your heart and brain health.
Aug 11, 2022
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Your teeth are like tiny time capsules—they have the potential to provide a wealth of information to scientists centuries in the future. For example, if you allow your plaque to harden into dental calculus (also known as ...
Dec 9, 2021
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