Mononuclear phagocytes can both promote and inhibit inflammation. An LMU team has now shown that individual phagocytes in the central nervous system can play both roles, sequentially adopting different phenotypes with distinct ...
Sep 11, 2018
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(HealthDay)—The cytokine M-CSF promotes survival of lung and liver mononuclear phagocytes to mediate host defense during bacterial pneumonia, according to an experimental study published in the June 15 issue of The Journal ...
Aug 4, 2016
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A discovery about how the body deals with the cholesterol contained within its dying cells has suggested an exciting new approach to control people's cholesterol levels – and thus their risk of developing heart disease.
Nov 20, 2015
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Sepsis is a feared complication in bacterial infections. Despite treatment with antibiotics this uncontrolled systemic inflammation is linked to a very high mortality rate because there is no treatment that could bring the ...
Jun 27, 2013
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A DNA-covered submicroscopic bead used to deliver genes or drugs directly into cells to treat disease appears to have therapeutic value just by showing up, researchers report.
May 15, 2012
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Deletion of a protein in white blood cells improves their ability to fight the bacteria staphylococcus aureus and possibly other infections in mice with chronic granulomatous disease (CGD), according to a National Institutes ...
Aug 1, 2013
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Brain metastases are common secondary complications of other types of cancer, particularly lung, breast and skin cancer. The body's own immune response in the brain is rendered powerless in the fight against these metastases ...
Sep 25, 2012
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