Inside cells, where DNA is packed tightly in the nucleus and rigid proteins keep intricate transport systems on track, some molecules have a simpler way of establishing order. They can self-organize, find one another in crowded ...
Aug 15, 2018
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Researchers have used computational models to understand what drives the accumulation of alpha-synuclein protein, a key culprit in the development of Parkinson's disease.
Apr 2, 2024
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A team of researchers led by Dr. Marcus Conrad from Helmholtz Munich has discovered a novel anti-cancer drug called icFSP1, which sensitizes cancer cells to ferroptosis. The results of this research are published in Nature.
Jun 28, 2023
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Researchers in UC Santa Barbara neuroscientist Kenneth S. Kosik's lab have discovered a novel organelle—a previously unknown cell structure whose function it is to help clean up faulty proteins in times of stress and keep ...
Jun 14, 2022
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Researchers at the University of North Carolina at Chapel Hill and the UNC Lineberger Comprehensive Cancer Center have uncovered a new mechanism that activates specific genes, leading to the development of cancers.
Jun 23, 2021
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A team of researchers at the Case Western Reserve University School of Medicine has taken a major step toward understanding the mechanisms involved in the formation of large clumps of tau protein, a hallmark of Alzheimer's ...
Dec 1, 2020
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Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.
Jun 3, 2020
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A study led by the IBB-UAB has identified the molecular mechanism through which a protein carrying genetic mutations associated with limb-girdle muscular dystrophy type 1G accelerates its tendency to form amyloid fibrils ...
Jan 29, 2020
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Cells regularly go through a process called autophagy—literally translated as 'self-eating' - which helps to destroy bacteria and viruses after infection.
Aug 21, 2019
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UT Southwestern researchers recently reported a basic science finding that might someday lead to better treatments for neurodegenerative diseases like a hereditary form of Lou Gehrig's disease.
Jun 14, 2018
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