Immunology

New target identified to combat deadly allergic reactions

Researchers in France have identified a molecular motor that controls the release of inflammatory factors that cause severe and fatal allergic reactions. The study, "Kinesin-1 controls mast cell degranulation and anaphylaxis ...

Neuroscience

How neurons talk to each other

Neurons are connected to each other through synapses, sites where signals are transmitted in the form of chemical messengers. Reinhard Jahn, Director at the Max Planck Institute for Biophysical Chemistry in Göttingen, has ...

HIV & AIDS

Study reveals how a Rab protein controls HIV-1 replication

HIV-1 replication requires the coordinated movement of the virus's components toward the plasma membrane of an immune cell, where the virions are assembled and ultimately released. A study in The Journal of Cell Biology reveals ...

Psychology & Psychiatry

Discovering why antidepressants don't work well for kids

Depression is a major health problem for which most patients are not effectively treated. In particular, depression is an increasing problem in children and teenagers. The most commonly prescribed antidepressants are selective ...

HIV & AIDS

Research captures transient details of HIV genome packaging

Once HIV-1 has hijacked a host cell to make copies of its own RNA genome and viral proteins, it must assemble these components into new virus particles. The orchestration of this intricate assembly process falls to a viral ...

Medical research

Understanding and improving the body's fight against pathogens

Scientists from A*STAR's Bioprocessing Technology Institute (BTI) have uncovered the crucial role of two signalling molecules, DOK3 and SHP1, in the development and production of plasma cells. These discoveries, published ...

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