Medical research

Researchers identify potential target in myeloid malignancies

Researchers at Children's Hospital of Philadelphia (CHOP) have identified a molecule that plays a role in post-translational modification and activation in myeloid malignancies, making it a potential therapeutic target. The ...

Neuroscience

How synaptic vesicles accumulate glutamate

In the brain, neurons communicate via neurotransmitters, which trigger electrical signals in downstream neurons by binding and activating specific receptors. Neurotransmitters are released through the fusion of synaptic vesicles, ...

Medical research

Palmitoylation, a new target for anti-cancer drugs

Peripheral membrane proteins temporarily bind to cell membranes, a necessary step for them to be able to fulfill their biological function. To do this, certain enzymes that catalyze their lipid modification come into action. ...

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Cell membrane

The cell membrane (also called the plasma membrane or plasmalemma) is the biological membrane separating the interior of a cell from the outside environment.

It is a semipermeable lipid bilayer found in all cells. It contains a wide variety of biological molecules, primarily proteins and lipids, which are involved in a vast array of cellular processes such as cell adhesion, ion channel conductance and cell signaling. The plasma membrane also serves as the attachment point for both the intracellular cytoskeleton and, if present, the extracellular cell wall.

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