Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have built and demonstrated the potential efficacy of a new chimeric antigen receptor (CAR) T-cell-based immunotherapy specifically designed to treat patients ...
Feb 16, 2024
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Many genetic mutations have been found to be associated with a person's risk of developing Parkinson's disease. Yet for most of these variants, the mechanism through which they act remains unclear.
Jan 27, 2021
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Drawing on X-ray crystallography and experimental data, as well as a software suite for predicting and designing protein structures, a UC Davis School of Medicine researcher has developed an algorithm that predicts what has ...
Dec 12, 2011
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Metastasizing cancer cells often express integrins that provide better traction. A new study in The Journal of Cell Biology reveals how a lipid-converting enzyme helps the cells mobilize these integrins.
Jan 23, 2012
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Body builders have it right: vitamin E does help build strong muscles, and scientists appear to have figured out one important way it does it.
May 19, 2015
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SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells. Professor Johanna Ivaska's research group at Turku Bioscience observed that SORLA functionally contributes ...
Jan 29, 2021
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Thyroid hormone resistance has been linked to mutations in the IGSF1 gene for the first time—surprising researchers who did not suspect it played a role in the maintenance of normal thyroid function.
Jan 16, 2013
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The outer membrane of sperm cells was first described as a result of the work by a Mexican biotechnologist.
Jan 14, 2015
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National Institutes of Health researchers used the popular anti-wrinkle agent Botox to discover a new and important role for a group of molecules that nerve cells use to quickly send messages. This novel role for the molecules, ...
May 2, 2013
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Peripheral membrane proteins temporarily bind to cell membranes, a necessary step for them to be able to fulfill their biological function. To do this, certain enzymes that catalyze their lipid modification come into action. ...
Apr 25, 2022
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