Medical research

Study implicates neural stem cell defects in smooth brain syndrome

Research led by scientists at UC San Francisco and Case Western Reserve University School of Medicine has used brain "organoids"—tiny 3-D models of human organs that scientists grow in a dish to study disease—to identify ...

Genetics

Induced pluripotent stem cells don't increase genetic mutations

It's been more than 10 years since Japanese researchers Shinya Yamanaka, M.D., Ph.D., and his graduate student Kazutoshi Takahashi, Ph.D., developed the breakthrough technique to return any adult cell to its earliest stage ...

Genetics

Gene key for chemically reprogramming human stem cells

Scientists have discovered the gene essential for chemically reprogramming human amniotic stem cells into a more versatile state similar to embryonic stem cells, in research led by UCL and Heinrich Heine University.

Genetics

CRISPR study reveals unexpected roles of non-coding RNAs

UC San Francisco researchers have taken a major step toward understanding the function of the tens of thousands of human genes that do not code for proteins, a phenomenon considered one of the key remaining mysteries of the ...

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