A preclinical study led by researchers at The University of Texas MD Anderson Cancer Center shows an antibody-drug conjugate (ADC) targeting surface protein MT1-MMP can act as a guided missile in eradicating osteosarcoma ...
Apr 12, 2021
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A potent and selective enhancer of zeste homolog 2 (EZH2) inhibitor IHMT-EZH2-115 was recently discovered by researchers led by Prof. Liu Qingsong from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences ...
Nov 1, 2021
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To reimagine existing preclinical trials for Alzheimer's disease, University of Pittsburgh School of Medicine neuroscientists created the first non-human primate model of hereditary Alzheimer's in marmoset monkeys, outlining ...
Sep 6, 2023
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A new research paper was published on the cover of Aging titled, "Effects of resveratrol on in vitro circadian clock gene expression in young and older human adipose-derived progenitor cells."
Jan 16, 2024
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The Xue Lab at the Hackensack Meridian Center for Discovery and Innovation (CDI) has made another breakthrough in better understanding and potentially modulating the immune system to fight diseases.
Jan 18, 2024
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This week, scientists from the A·WOL Consortium based at the Liverpool School of Tropical Medicine have published a paper entitled 'Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes ...
Mar 16, 2017
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An aging population will bring colossal health, social, and economic challenges over the coming decades. As people live longer, staving off the physical decline and frailty that come with age has become a holy grail, with ...
10 hours ago
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A new research paper titled "Deciphering reproductive aging in women using a NOD/SCID mouse model for distinct physiological ovarian phenotypes has been published in Aging.
Nov 7, 2023
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In preclinical models, combining an investigational Aurora Kinase A (AURKA) inhibitor with a KRAS inhibitor or a WEE1 inhibitor showed efficacy against lung cancer cells with intrinsic or acquired resistance to KRAS inhibition, ...
Oct 7, 2021
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Cholangiocarcinomas (CCAs) are a highly aggressive and diverse group of malignancies of the biliary tract that currently account for 15% of all liver cancers and approximately 3% of gastrointestinal tumors. While rare, the ...
Nov 29, 2022
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