On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, ...
Mar 22, 2024
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Nagoya University researchers and their colleagues in Japan have found that middle-age obesity is caused by age-related changes in the shape of neurons in the hypothalamus, a region of the brain that controls metabolism and ...
Mar 13, 2024
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An international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma (POAG), the most common type of glaucoma and the leading cause of irreversible ...
Feb 20, 2024
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Northwestern Medicine scientists have revealed how a gene considered essential for histone modification regulates skin development, according to a recent study published in Nature Communications.
Sep 6, 2023
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Reduced expression of specific calcium channels impaired electrical signaling between neurons and contributed to the onset of behaviors associated with neurodevelopmental disorders and seizure susceptibility in mouse models, ...
Jun 16, 2023
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Scientists at St. Jude Children's Research Hospital have identified how an appendage on the surface of cells, called the primary cilium, contributes to certain types of medulloblastoma. The study has implications for drug ...
Jul 8, 2022
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A new study from Karolinska Institutet and the Helmholtz Diabetes Research Center shows that primary cilia, hair-like protrusions on endothelial cells inside vessels, play an important role in the blood supply and delivery ...
Dec 4, 2020
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Structures called primary cilia—which act like TV antennas for cells to detect signals—are present in fewer numbers in mice born with Fragile X syndrome, according to researchers from The University of Texas Health Science ...
Jul 30, 2020
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UC San Francisco researchers have discovered that the brain's ability to regulate body weight depends on a novel form of signaling in the brain's "hunger circuit" via antenna-like structures on neurons called primary cilia.
Jan 8, 2018
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Understanding how cancer cells are able to metastasize—migrate from the primary tumor to distant sites in the body—and developing therapies to inhibit this process are the focus of many laboratories around the country. ...
Dec 15, 2017
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