Prions are fascinating, enigmatic, and might teach us not only about rare prion diseases like Creutzfeld-Jakob disease, mad cow disease, or scrapie, but also about other more common neurodgenerative diseases. Two studies ...
Jul 2, 2015
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Diagnosis of deadly brain conditions could be helped by new research that shows how infectious proteins that cause the disease spread.
Aug 4, 2015
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An article published in the journal PLOS Pathogens reports a realistic computational model for the structure and mechanism of replication of prions, infectious agents responsible for mad cow disease and other neurodegenerative ...
Jul 11, 2019
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Prion diseases are fatal and incurable neurodegenerative conditions of humans and animals. Yet, how prions kill nerve cells (or neurons) remains unclear. A study published on May 26, 2016 in PLOS Pathogens describes a system ...
May 26, 2016
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Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP. How these aggregates form within and kill brain cells ...
Dec 22, 2021
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A nasal brush test can rapidly and accurately diagnose Creutzfeldt-Jakob disease (CJD), an incurable and ultimately fatal neurodegenerative disorder, according to a study by National Institutes of Health (NIH) scientists ...
Aug 6, 2014
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(HealthDay)—Cerebrospinal fluid (CSF) real-time quaking-induced conversion (RT-QuIC) has high diagnostic specificity and sensitivity for prion diseases, according to a study published online Nov. 28 in the Annals of Neurology.
Dec 3, 2016
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In a new study NYU School of Medicine researchers report that they have found several chemical compounds, including an antidepressant, that have powerful effects against brain-destroying prion infections in mice, opening ...
Sep 14, 2011
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The earliest eye damage from prion disease takes place in the cone photoreceptor cells, specifically in the cilia and the ribbon synapses, according to a new study of prion protein accumulation in the eye by National Institutes ...
Jan 29, 2021
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New research published today, 10th July 2017, online in the journal Oncogene could offer hope to the thousands of, mainly young, people affected by the hereditary condition Neurofibromatosis 2 (NF2). This condition is characterised ...
Jul 9, 2017
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