Oncology & Cancer

Combining immunotherapies effective against mouse model of cancer

Rhabdomyosarcoma, a cancer made up of cells that normally develop into skeletal muscles, is the most common soft tissue cancer in children. If it is detected early and localized in certain areas, rhabdomyosarcoma is usually ...

Oncology & Cancer

Overall survival up for melanoma brain metastases

(HealthDay)—Overall survival (OS) for patients with melanoma brain metastases (MBM) has improved significantly since 2000, according to a study published online Oct. 12 in Cancer.

Medical research

Researchers uncover a new role of 'moonlighting' proteins

Although known to regulate fundamental cellular processes in humans, including cell growth, division and programmed cell death, the protein group known as chloride intracellular channel (CLIC) proteins is yet to be fully ...

Oncology & Cancer

Ovarian cancer: Potential therapeutic target identified

A gene called DOT1L appears to play a role in progression and severity of ovarian cancer, and inhibitors of the DOT1L enzyme may offer a new therapeutic approach for the disease, University of Alabama at Birmingham researchers ...

Immunology

Study identifies new mechanism for antibacterial immunity

The innate immune system serves as a first-line defense, responding to infections almost immediately after a pathogen makes its way into the body. This response is carried out in two major ways: the cell can amplify the message ...

Inflammatory disorders

Link found between cell death and inflammatory disease

(Medical Xpress)—A team of Melbourne researchers has shown a recently discovered type of cell death called necroptosis could be the underlying cause of inflammatory disease.

Neuroscience

Born to survive—How human neurons manage to live a century

Essentially all human tissues and organs have the capacity to heal, to renew cells which are damaged or killed. In this context, the human brain behaves fundamentally differently. The vast majority of nerve cells are created ...

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