The histone de-acetylase (HDAC) inhibitor panobinostat is able to target and destroy triple negative breast cancer, reveals a new study published in BioMed Central's open access journal Breast Cancer Research. Researchers ...
May 21, 2012
0
0
Programmed cell death is a mechanism that causes defective and potentially harmful cells to destroy themselves. It serves a number of purposes in the body, including the prevention of malignant tumor growth. Now, researchers ...
Dec 18, 2014
0
0
Patients with advanced melanoma skin cancer survive for longer without their disease progressing if they have been treated with a combination of two drugs, nivolumab and ipilimumab, than with either of these drugs alone. ...
Sep 28, 2015
0
20
Melbourne researchers have uncovered key steps involved in programmed cell death, offering new targets for the treatment of diseases including lupus, cancers and neurodegenerative diseases.
Oct 31, 2014
0
0
A*STAR researchers have clarified the role of one particular regulatory protein in controlling the development of plasma cells, opening up several new avenues toward clinical applications.
Apr 30, 2015
0
3
A protein called c-FLIP-R is critical to immune cell survival: If this molecule is missing, the cells kill themselves – and are thus no longer able to perform their job fighting off invaders. Now, scientists at the Helmholtz ...
May 31, 2013
0
0
Scientists have long known that organ size is shaped by many factors, including the size of each cell, proliferation, cell differentiation, death, and, of course, the total number of cells. However, the molecular mechanisms ...
Jul 31, 2018
0
7
Researchers from Charité—Universitätsmedizin Berlin have been able to improve their understanding of the key mechanism involved in the pathogenesis of a serious autoimmune disease. For the first time, researchers were ...
Nov 3, 2017
9
20
Gene therapies developed by University of Pennsylvania School of Veterinary Medicine researchers have worked to correct different forms of blindness. While effective, the downside to these approaches to vision rescue is that ...
Jan 16, 2014
0
0
A new study led by scientists at the University of Pennsylvania School of Veterinary Medicine has painted a clearer picture of the delicate arms race between the human immune system and a pathogen that seeks to infect and ...
May 5, 2014
0
0
