Intermittent parathyroid hormone treatment (iPTH) and mechanical loading through exercise have both been shown to stimulate bone formation. These osteoanabolic stimuli are partially mediated by G protein-coupled receptors. ...
Aug 9, 2016
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PGK1, a glycolytic enzyme, has been found to play a role in coordinating cellular processes crucial to cancer metabolism and brain tumor formation, according to results published in today's online issue of Molecular Cell. ...
Mar 3, 2016
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Researchers use induced pluripotent stem cells in a mouse model to show that diseased bone growth may be stimulated by a key molecule for inflammation. Inhibition of activin-A was found to repress the bone overgrowth typically ...
Nov 30, 2015
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Groundbreaking new reproductive research from the School of Medicine has identified key molecular events that could be playing a critical role as sperm and egg fuse to create new life. The findings might one day lead to the ...
Jun 23, 2015
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Diseases of the sensory or motile cilia play a key role in lung diseases or diabetes. Scientists at Helmholtz Zentrum München have now discovered the protein Flattop. It regulates the asymmetric positioning of cilia. Malfunctions ...
Oct 28, 2014
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(Medical Xpress)—Osteoporosis and aging-related bone loss is debilitating and painful. With a greater understanding of Wnt4 signaling, researchers are now closer to developing therapeutic agents that could slow down bone ...
Aug 12, 2014
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Prions can be notoriously destructive, spurring proteins to misfold and interfere with cellular function as they spread without control. New research, publishingin the open access journal PLOS Biology on February 11 2014, ...
Feb 11, 2014
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Scientists at Washington University School of Medicine in St. Louis have discovered what appears to be a potent stimulator of new bone growth. The finding could lead to new treatments for osteoporosis and other diseases that ...
Jan 30, 2014
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A newly discovered early-warning system triggers cellular suicide when a critical RNA editing system breaks down.
Dec 4, 2013
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Scientists from the Florida campus of The Scripps Research Institute (TSRI) have found a group of proteins essential to the formation of long-term memories.
Sep 12, 2013
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