The protein α-synuclein plays an important role in Parkinson's and other neurodegenerative diseases. Although a considerable amount is known about the structure of the protein within the Parkinson's-typical amyloid deposits, ...
Jan 26, 2016
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In this issue of the Journal of Clinical Investigation, researchers led by Scott Pruitt at Duke University and Merck Research Laboratories report on a human clinical trial in which modified dendritic cells, a component of ...
Jun 24, 2013
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A future vaccine providing protection against a wide range of coronaviruses that jump from their original animal hosts to humans—including SARS-CoV-2, the cause of COVID-19—may be possible, say Johns Hopkins Medicine ...
Feb 16, 2022
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An anti-cancer drug reverses memory deficits in an Alzheimer's disease mouse model, University of Pittsburgh Graduate School of Public Health researchers confirm in the journal Science.
May 23, 2013
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Alzheimer's disease is the most common dementia worldwide and it is characterized by learning impairment, memory loss, disorientation and anxiety, among other behavioral and psychological symptoms. Since Alois Alzheimer described ...
Nov 16, 2020
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Muscle withering can occur as part of the progression of many diseases, including cancer and muscular dystrophy, as well as during the normal aging process. Cellular organelles known as mitochondria provide energy for muscle ...
Mar 13, 2013
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An enzyme that could represent a powerful new tool for combating Alzheimer's disease has been discovered by researchers at Mayo Clinic in Florida. The enzyme—known as BACE2—destroys beta-amyloid, a toxic protein fragment ...
Sep 17, 2012
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The genome of the HIV-1 virus is protected by a conical-shaped protein shell called a capsid, which performs many functions crucial to viral infection—shielding the virus from the immune system, attaching to cell's transport ...
Aug 15, 2019
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A team of investigators has discovered a new, more powerful variant on an antimicrobial resistance gene common among Staphylococcus species. The gene protects the bacteria from an antiseptic compound widely used in healthcare. ...
Apr 15, 2019
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The plaque deposits in the brain of Alzheimer's patients are surrounded by the brain's own immune cells, the microglia. This was already recognized by Alois Alzheimer more than one hundred years ago. But until today it still ...
Apr 11, 2013
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