Medications

A 'smashing' solution for cancer therapy

Sometimes too much of a good thing is not good at all. Inhibiting the function of the PD-1 protein, which blocks immune function, has shown high therapeutic efficacy in cancer immunotherapy. However, when this function is ...

Immunology

How the thymus trains T cells to fight infections

T cells are a special class of white blood cells that patrol the body and attack infected or foreign tissue. They learn to distinguish friendly proteins from dangerous ones in an organ called the thymus. However, when T cells ...

Alzheimer's disease & dementia

Uncovering one of the driving forces of Alzheimer's disease

Alzheimer's disease, the most common form of dementia, currently has no cure or effective therapy, in part due to gaps in our understanding of how the progressive neurodegenerative disorder arises in the brain.

Medical research

A reference tissue atlas for the human kidney

A team of researchers including Jens Hansen, Rachel Sealfon, Rajastree Menon, and colleagues of the Kidney Precision Medicine Project, built on an existing specific human kidney tissue atlas relevant to health care at single-cell ...

Genetics

A subtle genetic change gives new clues about epilepsy

Sometimes, even the alteration of a single nucleotide in a gene can cause serious disease. In a young boy with epilepsy, this kind of mutation has not just affected the functioning of the protein in question—it could also ...

Medications

Researchers develop potential oral treatment for COVID-19

Eugenol, an oily liquid extracted from cloves and a Southeast Asian plant known as holy basil, has been effective in treating mice infected with COVID-19 in a laboratory study, according to newly published research results ...

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