Severe influenza virus infection is characterized by a strong inflammatory response and profuse viral replication in lungs. These viruses, such as the notorious avian flu, have a high rate of death and to date there are no ...
Jan 10, 2019
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Defects in the gene TREM2 are linked to increased risk of Alzheimer's disease. The gene is required to activate immune cells called microglia in the brain, which help to eliminate the neurotoxic deposits that are typical ...
Jan 8, 2019
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About one in every 5,000 babies is born without enteric neurons in the distal colon resulting in Hirschsprung's disease. Because of the missing neurons, contents of the gut cannot pass normally, resulting in constipation ...
Jan 8, 2019
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Our bodies hold roughly 14 trillion cells, each containing a nucleus with DNA measuring two meters long by 20 atoms wide. To fit inside each nucleus, DNA coils around specialized proteins. These spools of wrapped DNA inhibit ...
Jan 3, 2019
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St. Jude Children's Research Hospital scientists have discovered a subset of helper T cells that may help to redefine understanding and treatment of chronic, debilitating inflammatory disorders. The research appears today ...
Dec 21, 2018
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Fresh discoveries about a rare genetic disorder that affects mainly boys may inform the development of therapies to treat the condition.
Dec 12, 2018
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Mutations in the BRCA1 and BRCA2 genes pose a serious risk for breast and ovarian cancer because they endanger the genomic stability of a cell by interfering with homologous recombination repair (HR), a key mechanism for ...
Dec 3, 2018
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Who regulates the key regulator? The Research Center for Molecular Medicine of the Austrian Academy of Sciences reports online in the journal Science about a newly discovered mechanism by which RAS proteins, central to cancer ...
Nov 21, 2018
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How do individual developing cells choose and commit to their "identity"—to become, for example, an immune cell, or a muscle cell, or a neuron?
Nov 19, 2018
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Dublin, Ireland: An antibody that binds simultaneously to two distinct regions of the HER2 receptor to block the growth of cancer cells has shown promising signs of anti-tumour activity in a number of cancers including those ...
Nov 14, 2018
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