Medical research

Alternative splicing is crucial to muscle mass maintenance

Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don't fully understand the mechanisms that contribute to the maintenance of adult muscle mass.

Oncology & Cancer

Researchers peer inside cells to spy on cancer's on-off switch

Forty years after researchers first discovered it in fruit flies, a once-obscure cluster of proteins called PRC2 has become a key target for new cancer-fighting drugs, due to its tendency—when mutated—to bind to and silence ...

Neuroscience

In building the brain, cell pedigree matters

The cerebral cortex—the brain's epicenter of high-level cognitive functions, such as memory formation, attention, thought, language and consciousness—has fascinated neuroscientists for centuries.

Alzheimer's disease & dementia

How does alcohol influence the development of Alzheimer's disease?

Research from the University of Illinois at Chicago has found that some of the genes affected by alcohol and inflammation are also implicated in processes that clear amyloid beta—the protein that forms globs of plaques ...

Alzheimer's disease & dementia

Neuroscientists discover roles of gene linked to Alzheimer's

People with a gene variant called APOE4 have a higher risk of developing late-onset Alzheimer's disease: APOE4 is three times more common among Alzheimer's patients than it is among the general population. However, little ...

Oncology & Cancer

Genes of different importance for brain cancer

Two genes play important roles for the formation of malignant cancer in the brain. One gene prevents the formation of the tumour, while another gene promotes the tumour. This is shown in a new dissertation at Umeå University, ...

Genetics

New findings on autism-related disorder

In a study published today in Nature, Marc Bühler and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) have taken a major step forward in elucidating the mechanisms underlying a disorder known ...

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