Researchers from Boston University School of Medicine (BUSM) have discovered that the protein BRD4 could be an important new target to prevent castration-resistant prostate cancer metastases.
Jul 21, 2020
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(Medical Xpress)—The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author Honglin Zhou, MD, ...
Dec 20, 2012
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Protein p53 is known for controlling the life and death of a cell and has a key role in cancer research. P53 is known to be inactive in 50 percent of cancer patients. If researchers succeed in re-establishing the presence ...
Jan 20, 2012
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(Medical Xpress)—EPFL scientists have developed a "guide" that can be used to precisely predict the number of proteins a given gene will produce under varying conditions. This work will help biologists to engineer cells.
Aug 19, 2013
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The accumulation of one particular protein in the brain is the basis of three very different age-related conditions. Until recently, nobody understood how this was possible. Research by the Laboratory for Neurobiology and ...
Apr 29, 2020
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,Repeats of individual building blocks within proteins are the cause of many hereditary diseases, but how such repeats actually cause disease is still largely unknown. Researchers in Berlin investigated how repeat elongations ...
May 8, 2020
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Children with Down syndrome (DS) have an increased risk of developing leukemia, in particular acute megakaryoblastic leukemia (AMKL) and acute lymphoblastic leukemia (ALL). Through their studies in a mouse model of DS, a ...
Feb 22, 2012
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Melbourne researchers have discovered that acute myeloid leukaemia (AML), an aggressive blood cancer with poor prognosis, may be susceptible to medications that target a protein called Mcl-1.
Jan 17, 2012
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In a kind of molecular gymnastics, scientists at the University of North Carolina at Chapel Hill School of Medicine have devised a gene therapy cocktail that has the potential to treat some inherited diseases associated with ...
Aug 15, 2011
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Researchers from Karolinska Institutet in Sweden have found a protein that is a critical regulator in the development of fatty liver disease in mice, according to a study published in the journal Nature Communications.
Apr 11, 2019
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